Mychael V. Lourenco

Principal Investigator



Mychael has experience in cellular and molecular neuroscience and is specifically interested in molecular mechanisms of Alzheimer's disease. His training at the Fernanda De Felice and Sergio Ferreira’s labs led him to describe an inflammatory signaling that causes neuronal stress and memory loss in AD models. He further determined that anti-diabetic agents are neuroprotective in those models. Recently, his research described that the hormone FNDC5/irisin contributes to the beneficial action of physical exercise in AD models. Research in the lab aims to establish the molecular mechanisms of cognitive and mood dysfunction associated with neurological disease and propose potential targets for effective intervention.

 

Selected Awards

  • 2016  Finalist – 20th Young Talent Award in Life Sciences, Brazilian Society for Biochemistry and Molecular Biology, Brazil
     

  • 2017  Finalist – 21st Young Talent Award in Life Sciences, Brazilian Society for Biochemistry and Molecular Biology, Brazil
     

  • 2017  CAPES Award for Best PhD Dissertations in Brazil (2016), Brazilian Federal Foundation for Higher Education (CAPES) – Ministry of Education
     

  • 2017  Vital Brazil Best PhD Thesis Award – Biological, Health and Agricultural Sciences, Brazilian Federal Foundation for Higher Education (CAPES) – Ministry of Education

  • 2017 - 1st SBBq/Biozeus Innovation Prize, Brazilian Society for Biochemistry and Molecular Biology, Brazil
     

  • 2020 - Young IBRO Regions Connecting Award - International Brain Research Organization
     

  • 2021 - Affiliate Member of the Brazilian Academy of Sciences

Mychael received his B.Sc. degree in Genetics (2010), his MSc (2012) and PhD (2016) from the Federal University of Rio de Janeiro. He further conducted postdoctoral training at the same university. He was a visiting collaborator at Columbia University (New York) and is an Assistant Professor of Neuroscience at the Institute of Medical Biochemistry Leopoldo de Meis (Federal University of Rio de Janeiro).

He is a member of the Young Scientist Steering Committee of the International Society for Neurochemistry (2017-2021), and an affiliate member of the Molecular and Cellular Cognition Society since 2013.He served as a member of the Trainee Advisory Committee (2016-2019) and the Online Program Steering Committee (2017-2021) of the Society for Neuroscience.

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